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Motif ID: SOX{8,9,10}.p2

Z-value: 0.945

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_105511615	1.679	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chr6_-_128883125	1.197	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr2_+_101680594	1.013	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr20_-_38751289	0.844	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_-_117011824	0.833	NM_001007237 NM_001542	IGSF3	immunoglobulin superfamily, member 3
chr12_+_52665196	0.759	NM_017409	HOXC10	homeobox C10
chr1_-_12599934	0.684	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr10_-_123346148	0.645	NM_001144915	FGFR2	fibroblast growth factor receptor 2
chr17_-_37196463	0.642	NM_002230 NM_021991	JUP	junction plakoglobin
chr20_-_39680405	0.641	NM_032221	CHD6	chromodomain helicase DNA binding protein 6
chr11_-_27450808	0.616	NM_018490	LGR4	leucine-rich repeat containing G protein-coupled receptor 4
chr19_+_12810258	0.603	NM_014975	MAST1	microtubule associated serine/threonine kinase 1
chr17_+_44325127	0.596	NM_001002027 NM_005175	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr6_-_10523424	0.579	NM_003220	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr16_-_30841938	0.579		NCRNA00095	non-protein coding RNA 95
chr6_+_132000134	0.576	NM_005021	ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3
chr20_+_29656744	0.573	NM_002165 NM_181353	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr16_+_21518633	0.572		METTL9	methyltransferase like 9
chr8_-_29262240	0.556	NM_057158	DUSP4	dual specificity phosphatase 4
chr16_+_67698943	0.554	NM_005329	HAS3	hyaluronan synthase 3
chr11_-_16380967	0.543	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr1_+_154855709	0.535	NM_021817	HAPLN2	hyaluronan and proteoglycan link protein 2
chr7_+_121300394	0.534	NM_002851	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr2_+_220200530	0.533	NM_005070 NM_201574	SLC4A3	solute carrier family 4, anion exchanger, member 3
chr5_-_50714836	0.530		LOC642366	hypothetical LOC642366
chr1_-_155095289	0.526	NM_014215	INSRR	insulin receptor-related receptor
chr10_-_32707549	0.519		EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr14_-_89490780	0.517	NM_145231	EFCAB11	EF-hand calcium binding domain 11
chr17_-_36074812	0.513	NM_152349	KRT222	keratin 222
chr11_+_101488380	0.508	NM_001195045	YAP1	Yes-associated protein 1
chr20_+_3775421	0.501	NM_020746	MAVS	mitochondrial antiviral signaling protein
chr19_+_63482118	0.492	NM_021089	ZNF8	zinc finger protein 8
chr10_-_91451102	0.492		NBAS	neuroblastoma amplified sequence
chr12_-_23995220	0.474		SOX5	SRY (sex determining region Y)-box 5
chr12_-_23995109	0.472		SOX5	SRY (sex determining region Y)-box 5
chr1_+_93686154	0.471	NM_001024948 NM_001164473 NM_017737	FNBP1L	formin binding protein 1-like
chr17_+_16886491	0.468	NM_015134 NM_201274	MPRIP	myosin phosphatase Rho interacting protein
chr6_-_28663045	0.457	NM_052923	SCAND3	SCAN domain containing 3
chr18_+_3437607	0.453	NM_173207	TGIF1	TGFB-induced factor homeobox 1
chr16_-_30705707	0.449	NM_001080417	ZNF629	zinc finger protein 629
chr1_-_2451543	0.446	NM_001010926	HES5	hairy and enhancer of split 5 (Drosophila)
chr5_+_76047536	0.445	NM_001992	F2R	coagulation factor II (thrombin) receptor
chr1_+_64012154	0.441	NM_001083592 NM_005012	ROR1	receptor tyrosine kinase-like orphan receptor 1
chr5_+_50714996	0.441		ISL1	ISL LIM homeobox 1
chr19_-_60369731	0.436	NM_178837	C19orf51	chromosome 19 open reading frame 51
chr2_-_204108151	0.433	NM_203365 NM_213589	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr5_-_16989290	0.429		MYO10	myosin X
chr20_-_538909	0.427	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr18_-_13905534	0.425	NM_000529	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)
chr15_+_38923470	0.422	NM_003710 NM_181642	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr9_-_73573121	0.418	NM_001135820 NM_013390	TMEM2	transmembrane protein 2
chr14_+_36196523	0.415	NM_006194	PAX9	paired box 9
chr14_+_23008742	0.407		NGDN	neuroguidin, EIF4E binding protein
chr16_-_19440786	0.405	NM_016641	GDE1	glycerophosphodiester phosphodiesterase 1
chr6_-_64087806	0.401	NM_001143940 NM_016571	LGSN	lengsin, lens protein with glutamine synthetase domain
chr3_-_48675321	0.398	NM_001407	CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr2_+_172658453	0.397	NM_001038493 NM_178120	DLX1	distal-less homeobox 1
chr6_+_83129641	0.397	NM_006670	TPBG	trophoblast glycoprotein
chr1_+_158636987	0.395	NM_020335	VANGL2	vang-like 2 (van gogh, Drosophila)
chr1_+_200449905	0.384	NM_001017404	LGR6	leucine-rich repeat containing G protein-coupled receptor 6
chr2_-_37752272	0.381		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr14_+_23008723	0.374	NM_001042635 NM_015514	NGDN	neuroguidin, EIF4E binding protein
chr2_+_74539039	0.373	NM_012477	WBP1	WW domain binding protein 1
chr11_-_101828563	0.373	NM_052932	TMEM123	transmembrane protein 123
chr2_-_70329067	0.372	NM_022037 NM_022173	TIA1	TIA1 cytotoxic granule-associated RNA binding protein
chr18_+_3584056	0.371		FLJ35776	hypothetical LOC649446
chr19_+_17440577	0.368		SLC27A1	solute carrier family 27 (fatty acid transporter), member 1
chr6_-_42218692	0.367	NM_001164446	C6orf132	chromosome 6 open reading frame 132
chr18_+_3441589	0.366	NM_170695 NM_173210	TGIF1	TGFB-induced factor homeobox 1
chr20_+_16676997	0.363	NM_020157	OTOR	otoraplin
chr10_-_115924353	0.359	NM_018017	C10orf118	chromosome 10 open reading frame 118
chr10_+_124885556	0.358	NM_001105574	HMX3	H6 family homeobox 3
chr14_-_90953883	0.358	NM_001080414	CCDC88C	coiled-coil domain containing 88C
chr15_+_38923914	0.358	NM_001032367	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr20_+_20296744	0.357	NM_002196	INSM1	insulinoma-associated 1
chr22_+_38652555	0.355		GRAP2	GRB2-related adaptor protein 2
chr11_-_57173823	0.354	NM_145008	YPEL4	yippee-like 4 (Drosophila)
chr14_+_38714111	0.353	NM_002687	PNN	pinin, desmosome associated protein
chr6_+_30796064	0.352		TUBB	tubulin, beta
chr5_+_50714714	0.350	NM_002202	ISL1	ISL LIM homeobox 1
chr6_-_80303822	0.350	NM_001122769 NM_181714	LCA5	Leber congenital amaurosis 5
chr3_+_51397731	0.344	NM_006010	MANF	mesencephalic astrocyte-derived neurotrophic factor
chr9_+_19398924	0.343	NM_001010887	ACER2	alkaline ceramidase 2
chr3_-_150422474	0.341	NM_000096	CP	ceruloplasmin (ferroxidase)
chr14_-_54948290	0.341	NM_014924	ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)
chr13_+_28900776	0.338	NM_015233	MTUS2	microtubule associated tumor suppressor candidate 2
chr22_+_37193961	0.331	NM_006855 NM_016657	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr1_-_16411690	0.331	NM_153213	ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19
chr14_+_58725104	0.329	NM_014992	DAAM1	dishevelled associated activator of morphogenesis 1
chr9_-_32540818	0.326		TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr13_+_51927615	0.325		CKAP2	cytoskeleton associated protein 2
chr9_+_22103542	0.323		CDKN2B-AS1	CDKN2B antisense RNA 1 (non-protein coding)
chr5_-_16989371	0.322	NM_012334	MYO10	myosin X
chr8_+_79740813	0.322	NM_016010	FAM164A	family with sequence similarity 164, member A
chr4_+_74491272	0.320		ALB	albumin
chr2_+_223244606	0.317	NM_058165	MOGAT1	monoacylglycerol O-acyltransferase 1
chr5_+_40877053	0.315	NM_032587	CARD6	caspase recruitment domain family, member 6
chr12_-_80677223	0.313	NM_003625	PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr20_-_21326046	0.309	NM_033176	NKX2-4	NK2 homeobox 4
chr8_+_70541412	0.308	NM_001128204 NM_015170	SULF1	sulfatase 1
chr11_-_14870326	0.304	NM_024514	CYP2R1	cytochrome P450, family 2, subfamily R, polypeptide 1
chr3_-_129777618	0.304	NM_007354	C3orf27	chromosome 3 open reading frame 27
chr2_-_151052391	0.304	NM_005168	RND3	Rho family GTPase 3
chr10_+_91451313	0.303	NM_016195	KIF20B	kinesin family member 20B
chr3_+_142143329	0.303	NM_001104647 NM_018155	SLC25A36	solute carrier family 25, member 36
chr6_-_10523203	0.301		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_-_130578110	0.300	NM_152552	SAMD3	sterile alpha motif domain containing 3
chr3_+_85090721	0.297	NM_001167674 NM_001167675	CADM2	cell adhesion molecule 2
chr21_-_18113514	0.297	NM_001100420 NM_001100421 NM_017447	C21orf91	chromosome 21 open reading frame 91
chr1_+_29113589	0.297	NM_001166006	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr16_-_24934151	0.297	NM_001006634 NM_018054	ARHGAP17	Rho GTPase activating protein 17
chr17_-_46298671	0.296		TOB1	transducer of ERBB2, 1
chr17_-_40380553	0.293	NM_001080443	KIF18B	kinesin family member 18B
chr2_+_12775814	0.292
chr14_-_64638809	0.290		MAX	MYC associated factor X
chr2_+_62787534	0.290	NM_001142614	EHBP1	EH domain binding protein 1
chr6_+_50894397	0.289	NM_003221	TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr3_+_51397756	0.289		MANF	mesencephalic astrocyte-derived neurotrophic factor
chr12_-_102413875	0.288	NM_198521 NM_001099336	C12orf42	chromosome 12 open reading frame 42
chr9_+_4782833	0.288	NM_005772	RCL1	RNA terminal phosphate cyclase-like 1
chr8_+_70541631	0.285		SULF1	sulfatase 1
chr2_+_201755865	0.284	NM_001230 NM_032974 NM_032977	CASP10	caspase 10, apoptosis-related cysteine peptidase
chr2_-_201536425	0.281	NM_006190	ORC2	origin recognition complex, subunit 2
chr14_-_30746577	0.280
chr3_-_107070400	0.278	NM_170662	CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr3_+_195336625	0.278	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr2_+_220017617	0.277		SPEG	SPEG complex locus
chr14_-_19871267	0.276	NM_021178 NM_182849	CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr14_-_30565275	0.275	NM_001083893 NM_014574	STRN3	striatin, calmodulin binding protein 3
chr15_-_62460622	0.271	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr3_+_112743729	0.271		CD96	CD96 molecule
chr8_-_22044463	0.270	NM_005144 NM_018411	HR	hairless homolog (mouse)
chr1_-_152431175	0.270	NM_152263	TPM3	tropomyosin 3
chr2_-_164300758	0.269	NM_018086	FIGN	fidgetin
chr2_+_17923404	0.269	NM_002252	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr4_+_119174947	0.268	NM_004784	NDST3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr17_+_75366524	0.267	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr3_-_49117169	0.266	NM_005051	QARS	glutaminyl-tRNA synthetase
chr8_+_102573837	0.266	NM_024915	GRHL2	grainyhead-like 2 (Drosophila)
chr2_+_190981257	0.264	NM_017694	MFSD6	major facilitator superfamily domain containing 6
chr17_-_76985538	0.263
chr6_+_30796121	0.263		TUBB	tubulin, beta
chr5_-_41546384	0.262	NM_001005473	PLCXD3	phosphatidylinositol-specific phospholipase C, X domain containing 3
chr12_-_97812633	0.262		ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B
chr3_-_88190737	0.260	NM_001008390 NM_003663	CGGBP1	CGG triplet repeat binding protein 1
chr9_-_138778780	0.260	NM_203347	LCN15	lipocalin 15
chr10_-_105982052	0.259	NM_025145	WDR96	WD repeat domain 96
chr14_-_70345485	0.257	NM_033141	MAP3K9	mitogen-activated protein kinase kinase kinase 9
chr12_-_61283474	0.256	NM_175895	C12orf61	chromosome 12 open reading frame 61
chr5_+_140709907	0.256	NM_018922 NM_032095	PCDHGB1	protocadherin gamma subfamily B, 1
chr14_+_62740878	0.256	NM_020663	RHOJ	ras homolog gene family, member J
chr5_+_170668892	0.255	NM_021025	TLX3	T-cell leukemia homeobox 3
chr9_+_80101810	0.252	NM_021154 NM_058179	PSAT1	phosphoserine aminotransferase 1
chr10_-_99084417	0.251	NM_012083	FRAT2	frequently rearranged in advanced T-cell lymphomas 2
chr11_-_78829342	0.248	NM_001098816	ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)
chr6_+_30796123	0.247	NM_178014	TUBB	tubulin, beta
chr2_-_128285214	0.246	NM_001006622 NM_001006623 NM_018383	WDR33	WD repeat domain 33
chr3_-_198509808	0.246	NM_001098424 NM_004087	DLG1	discs, large homolog 1 (Drosophila)
chr7_-_27171673	0.245	NM_152739	HOXA9	homeobox A9
chr7_-_92686773	0.243	NM_198151	HEPACAM2	HEPACAM family member 2
chr3_-_101077605	0.243	NM_014890	FILIP1L	filamin A interacting protein 1-like
chrX_+_152565849	0.242		DUSP9	dual specificity phosphatase 9
chr20_+_1132097	0.242	NM_001009612	C20orf202	chromosome 20 open reading frame 202
chr6_-_2785682	0.242		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr16_-_52877829	0.239		IRX3	iroquois homeobox 3
chr20_+_10363949	0.238	NM_001009608	C20orf94	chromosome 20 open reading frame 94
chr19_-_6718417	0.238	NM_005490	SH2D3A	SH2 domain containing 3A
chr14_-_63830830	0.238	NM_001040275 NM_001437	ESR2	estrogen receptor 2 (ER beta)
chr21_-_33935883	0.237	NM_145858	CRYZL1	crystallin, zeta (quinone reductase)-like 1
chr7_-_27171648	0.236		HOXA9	homeobox A9
chr1_+_226404037	0.236	NM_020435	GJC2	gap junction protein, gamma 2, 47kDa
chr6_-_116681863	0.235	NM_021648	TSPYL4	TSPY-like 4
chr2_-_119322228	0.234	NM_001426	EN1	engrailed homeobox 1
chr20_-_13567529	0.233	NM_017714	TASP1	taspase, threonine aspartase, 1
chr3_+_188131209	0.233		ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr14_-_20807346	0.232	NM_001077442 NM_001077443 NM_004500 NM_031314	HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr10_-_134449467	0.231	NM_177400	NKX6-2	NK6 homeobox 2
chr1_+_85819004	0.231	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr7_-_92693716	0.231	NM_001039372	HEPACAM2	HEPACAM family member 2
chr16_+_81218142	0.228		CDH13	cadherin 13, H-cadherin (heart)
chr9_+_4782974	0.228		RCL1	RNA terminal phosphate cyclase-like 1
chr12_-_69289889	0.226	NM_002837	PTPRB	protein tyrosine phosphatase, receptor type, B
chr17_+_71095733	0.226		MYO15B	myosin XVB pseudogene
chr11_+_22316242	0.225	NM_020346	SLC17A6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr5_-_88004891	0.224		LOC645323	hypothetical LOC645323
chr4_-_101658094	0.224	NM_001159694 NM_016242	EMCN	endomucin
chr9_-_74757735	0.221	NM_000689	ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr20_-_42457717	0.221
chr16_+_24459173	0.220		RBBP6	retinoblastoma binding protein 6
chr2_+_198377561	0.220	NM_006226	PLCL1	phospholipase C-like 1
chr2_-_128285136	0.219		WDR33	WD repeat domain 33
chr20_-_33793286	0.219		RBM39	RNA binding motif protein 39
chr3_-_27739201	0.218		EOMES	eomesodermin
chrX_+_15428820	0.218	NM_203281	BMX	BMX non-receptor tyrosine kinase
chr5_-_134899537	0.216	NM_006161	NEUROG1	neurogenin 1
chr6_+_122762384	0.216	NM_001135564 NM_004506	HSF2	heat shock transcription factor 2
chr4_-_40211324	0.215		RBM47	RNA binding motif protein 47
chr13_+_51927495	0.215	NM_001098525 NM_018204	CKAP2	cytoskeleton associated protein 2
chr6_-_27222556	0.215	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr1_+_32512298	0.215	NM_001042771	LCK	lymphocyte-specific protein tyrosine kinase

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.17	2.42e-05	GO:0050794	regulation of cellular process
1.15	1.00e-04	GO:0050789	regulation of biological process
1.14	1.39e-04	GO:0065007	biological regulation
1.24	4.47e-04	GO:0032502	developmental process
1.24	1.16e-03	GO:0007275	multicellular organismal development
1.08	1.68e-03	GO:0009987	cellular process
1.24	2.13e-03	GO:0016043	cellular component organization
1.18	2.73e-03	GO:0032501	multicellular organismal process
1.28	3.71e-03	GO:0071842	cellular component organization at cellular level
1.20	5.09e-03	GO:0051716	cellular response to stimulus
1.36	5.92e-03	GO:0006996	organelle organization
1.15	7.01e-03	GO:0050896	response to stimulus
1.52	8.76e-03	GO:0051128	regulation of cellular component organization
1.45	1.02e-02	GO:0022607	cellular component assembly
1.23	1.12e-02	GO:0048856	anatomical structure development
1.24	1.76e-02	GO:0048731	system development
1.21	1.79e-02	GO:0071840	cellular component organization or biogenesis
1.67	2.60e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.51	2.99e-02	GO:0071844	cellular component assembly at cellular level
2.47	3.02e-02	GO:0034728	nucleosome organization
1.73	3.18e-02	GO:0007264	small GTPase mediated signal transduction
1.24	3.30e-02	GO:0071841	cellular component organization or biogenesis at cellular level
2.53	4.40e-02	GO:0006334	nucleosome assembly
1.39	4.63e-02	GO:0010604	positive regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.21	8.20e-07	GO:0005634	nucleus
1.08	7.29e-05	GO:0005622	intracellular
1.08	8.72e-05	GO:0044424	intracellular part
1.32	1.20e-03	GO:0031981	nuclear lumen
1.09	1.66e-03	GO:0043226	organelle
1.29	2.04e-03	GO:0044428	nuclear part
1.09	2.31e-03	GO:0043229	intracellular organelle
1.10	2.71e-03	GO:0043227	membrane-bounded organelle
1.10	2.76e-03	GO:0043231	intracellular membrane-bounded organelle
1.36	6.12e-03	GO:0005654	nucleoplasm
2.84	1.35e-02	GO:0000786	nucleosome
1.25	1.59e-02	GO:0043233	organelle lumen
1.24	2.09e-02	GO:0031974	membrane-enclosed lumen
1.81	3.95e-02	GO:0000785	chromatin

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.13	1.93e-03	GO:0005515	protein binding
1.38	4.43e-02	GO:0001071	nucleic acid binding transcription factor activity
1.38	4.43e-02	GO:0003700	sequence-specific DNA binding transcription factor activity

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